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Molecular co-accessibility identifies coordinated regulation between distant cis-regulatory elements
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DOI：10.1016/j.molcel.2026.07.020.png)
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Abstract
En 中文
• Simultaneous quantification of chromatin accessibility at multiple cis-regulatory elements • Co-accessibility identifies functional dependencies between cis-regulatory elements • Co-accessible elements are enriched for specific TF motifs and 3D chromatin contacts • Co-accessible elements show concerted accessibility changes across cell states
Keywords:
gene regulation
single-molecule genomics
long-read sequencing
single-molecule footprinting
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16.6
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1.0W
Citations:
8.5W
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Cited Papers