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Molecularly imprinted polymers for solid-phase extraction and solid-phase microextraction:: Recent developments and future trends
DOI:10.1016/j.chroma.2006.08.095.png)
摘要
En 中文
Molecularly imprinted polymers (MIPs) are synthetic polymers having a predetermined selectivity for a given analyte, or group of structurally related compounds, that make them ideal materials to be used in separation processes. In this sense, during past years a huge amount of papers have been published dealing with the use of MIF's as sorbents in solid-phase extraction, namely molecularly imprinted solid-phase extraction (MISPE). Although the majority of these papers were restricted to describe the use of different templates for different applications, several attempts proposing new alternatives to minimize the inherent drawbacks of the preparation and use of MIPs (i.e. template bleeding, tedious synthesis procedure, etc.) have been reported. Thus, this paper does not pretend to be a collection of MISPE-related papers but to give an overview on the significant attempts carried out during recent years to improve the performance of MIPs in solid-phase extraction. In addition, the use of MlPs packed in high performance liquid chromatography (HPLC) columns for the direct injection of crude sample extracts and the preparation of imprinted fibres for solid-phase microextraction will be also discussed. (C) 2006 Elsevier B.V. All rights reserved.
Keyword:
molecularly imprinted polymers
solid-phase extraction
direct injection
solid-phase microextraction
review
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IF:
4
论文数:
3.2W
被引数:
5.0W
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