.png){kind=icon}
.png){kind=icon}
Return
Multicellular ecosystems: Linking cellular diversity to tissue function and disease
.png){kind=icon}
OA
AI
Q
F
Y
Z
DOI：10.1016/j.tcb.2026.06.005.png)
.png){kind=icon}
.png){kind=icon}
Share.png){kind=icon}
Save
Abstract
En 中文
Single-cell and spatial genomics reveal tissues as dynamic multicellular ecosystems rather than static cell catalogs. Multicellular ecosystems and interaction patterns provide an organizational framework, linking local cell–cell communication to tissue-level states. Multicellular ecosystems exhibit context-dependent changes in cellular composition and interactions across physiological and disease conditions. An ecosystem perspective enables translational strategies, including patient stratification based on multicellular states and therapies targeting cellular niches and interactions.
Keywords:
multicellular coordination
single-cell and spatial genomics
cellular census
computational frameworks
translational systems medicine
AI Summary
Key information extracted from the uploaded paper, including a brief overview, abstract, background, key highlights, visual analysis, and future outlook.
Journal
IF:
18.1
Papers:
3.1K
Citations:
2.0W
Organization
Cited Papers