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Multiparametric Flow Cytometry Immune Profiling of Pulmonary and Extra-Pulmonary Tuberculosis Reveals Distinct Blood-Based Biomarker Signatures

delete2026-07-09
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PRE
AI
K
Kalaiarasan Ellappan
N
Noyal Mariya Joseph *
P
Prakash Babu Narasimhan
H
Harriet N. Garlant
S
Seshadri Vasan
K
Komal Jain
S
Saka Vinod Kumar
V
Vishnukanth Govindaraj
V
Vir Singh Negi
K
Karen E. Kempsell *
DOI：10.1016/j.tube.2026.102795delete
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Abstract

Abstract

En 中文
• Pulmonary TB and extrapulmonary TB exhibit distinct immune cell and biomarker profiles. • Identified biomarkers represent promising candidates for blood-based diagnosis of active TB. • Multicolour flow cytometry is a powerful tool for immunophenotyping in TB. • Blood-based immune markers identified by Multicolour flow cytometry show potential utility for differential TB diagnosis

Journal

Tuberculosis cover
Tuberculosis
IF:
2.9
Papers:
147
Citations:
3.6K

Organization

J
Jawaharlal Institute of Postgraduate Medical Education and Research
Scholars:
263
Papers: 102
Citations: 49
U
UK Health Security Agency
Scholars:
622
Papers: 150
Citations: 753
S
School of Medical and Health Sciences
Scholars:
93
Papers: 42
Citations: 0
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