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MULTIPLE HUMAN BETA-INTERFERON GENES

delete1982-09-01
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A
Anurag D. Sagar
P
Pravinkumar B. Sehgal
D
Doris L. Slate
F
F.H. Ruddle
DOI:10.1084/jem.156.3.744delete
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摘要

摘要

En 中文
Analysis of human .beta. interferon (IFN) mRNA preparations obtained from poly(I .cntdot. C)-induced human diploid fibroblasts (FS-4) and from several similarly induced human-mouse somatic cell hybrids by electrophoresis through agarose-CH3HgOH tube gels led to the detection of at least 5 translationally active human IFN-.beta. mRNA species. The results obtained are consistent with the existence of IFN-.beta. genes on different human chromosomes. Marked cell-dependent variability in the expression of these IFN mRNA species was observed.
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期刊

J
Journal of Experimental Medicine
IF:
10.6
论文数:
2.4W
被引数:
6.2W

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