.png){kind=icon}
返回
Multiple sclerosis lesion quantification using fuzzy-connectedness principles
.png){kind=icon}
PRE
AI
DOI：10.1109/42.640750.png)
.png){kind=icon}
原文求助.png){kind=icon}
分享.png){kind=icon}
收藏
摘要
En 中文
Multiple sclerosis (MS) is a disease of the white matter. Magnetic resonance imaging (MRI) is proven to be a sensitive method of monitoring the progression of this disease and of its changes due to treatment protocols. Quantification of the severity of the disease through estimation of MS lesion volume via MR imaging is vital for understanding and monitoring the disease and its treatment. This paper presents a novel methodology and a system that ran be routinely used for segmenting and estimating the volume of MS lesions via dual-echo fast spin-echo MR imagery, A recently developed concept of fuzzy objects forms the basis of this methodology. An operator indicates a few points in the images by pointing to the white matter, the grey matter, and the cerbro-spinal fluid (CSF), Each of these objects is then detected as a fuzzy connected set, The holes in the union of these objects correspond to potential lesion sites which are utilized to detect each potential lesion as a three-dimensional (3-D) fuzzy connected object These objects are presented to the operator who indicates acceptance/rejection through the click of a mouse button. The number and volume of accepted lesions is then computed and output. Based on several evaluation studies, we conclude that the methodology is highly reliable and consistent, with a coefficient of variation (due to subjective operator actions) of 0.9% (based on 20 patient studies, three operators, and two trials) for volume and a mean false-negative volume fraction of 1.3%, with a 95% confidence interval of 0%-2.8% (based on ten patient studies).
Keyword:
fuzzy connectedness
image segmentation
lesion detection
multiple sclerosis
MR image analysis
AI总结
对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。
期刊
IF:
9.8
论文数:
6.2K
被引数:
3.7W
机构
暂无机构信息
引用论文
ANALYSIS OF BRAIN AND CEREBROSPINAL-FLUID VOLUMES WITH MR IMAGING .1. METHODS, RELIABILITY, AND VALIDATION.png)
RADIOLOGY
RADIOLOGYIF15.2
PREAI
分享收藏Intra- and inter-observer agreement of brain MRI lesion volume measurements in multiple sclerosis - A comparison of techniques多发性硬化症中脑MRI病变体积测量的观察者内和观察者间一致性-技术的比较BRAIN
BRAINIF11.7
PREAI
分享收藏
查看更多内容