.png){kind=icon}
.png){kind=icon}
Return
Near-infrared fluorescent probes for super-resolution imaging
.png){kind=icon}
PRE
AI
L
P
W
G
W
F
J
L
DOI：10.2306/scienceasia1513-1874.2026.008.png)
.png){kind=icon}
Original request for help.png){kind=icon}
Share.png){kind=icon}
Save
Abstract
En 中文
During the past two decades, super-resolution microscopies (SRMs) have become powerful tools to resolve subcellular structures in a range of 10 nm to 100 nm. Progress in developing fluorescent probes is indispensable for the advancements in SRMs. However, it remains challenging to recognize and observe the bio-complexes in deep imaging depth with high resolution. The emergence of near-infrared (NIR) fluorescent probes brings new light for super-resolution fluorescent imaging due to less light scattering, decreased background signals of auto-fluorescence and low phototoxicity. Thus, in recent years, significant efforts have been made in the development of NIR fluorescence probes for visualizing the fine structures and organizations in cells with high resolution and excellent signal-to-noise ratio. Here we reviewed the recent progress in NIR probes that have been successfully applied to SRMs, including fluorescent proteins, molecular probes, and fluorescent nanomaterials. We also provided a potential prospect on the requirements in future development of NIR fluorescent probes for SRM applications.
Keywords:
near-infrared fluorescent probes
super-resolution imaging
biological applications
Journal
S
IF:
0.6
Papers:
75
Citations:
969
Organization
Cited Papers