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Neural tube morphogenesis
DOI:10.1016/S0959-437X(97)80078-0.png)
摘要
En 中文
Many important findings in the past year have helped to identify multiple cellular interactions and signals in vertebrates that govern induction of neuroectoderm, its patterning, neural tube formation, and the subsequent differentiation of neurons. For example, the neural inducers have been shown to function as inhibitors of BMP signaling, the roles of bone morphogenetic proteins and Sonic hedgehog during dorso-ventral specification of the neural tube have been further elucidated and the realization of a dorso-ventral inversion of the body axis contributed to a better understanding of evolutionarily related genes and functions between vertebrates and invertebrates.
Keyword:
PROTEIN-KINASE-A
DEVELOPING SPINAL-CORD
SONIC-HEDGEHOG
FLOOR PLATE
ECTOPIC EXPRESSION
SIGNALING PATHWAY
CHICK HOMOLOG
AVIAN EMBRYO
GENE
DIFFERENTIATION
期刊
C
IF:
3.6
论文数:
2.9K
被引数:
6.9K
机构
暂无机构信息
引用论文
Decreased signaling competence as a result of receptor overexpression: overexpression of CD4 reduces its ability to activate p56lck tyrosine kinase and to regulate T-cell antigen receptor expression in immature CD4+CD8+ thymocytes.受体过表达导致的信号传导能力降低: CD4的过表达降低了其激活p56lck酪氨酸激酶和调节未成熟CD4 CD8胸腺细胞中T细胞抗原受体表达的能力。

