Next-Generation Sequencing Completion and Timeliness Using a Reflex Testing Protocol for Patients with Stage II-IV Non-Squamous, Non-Small Cell Lung Cancer

Gordon Smilnak

doi:10.1016/j.cllc.2026.06.012

Next-Generation Sequencing Completion and Timeliness Using a Reflex Testing Protocol for Patients with Stage II-IV Non-Squamous, Non-Small Cell Lung Cancer

2026-07-02

0

PRE

AI

G

Gordon Smilnak

R

Rishika Singh

S

Sean C. Dougherty

S

Shipra Maheshwari

V

Vanessa L. Smith

E

Edward B. Stelow

D

Debamita Kundu

R

Ruyun Jin

R

Richard D. Hall

R

Ryan D. Gentzler *

DOI：10.1016/j.cllc.2026.06.012

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Next-Generation Sequencing (NGS) is critical for providing treatment recommendations across multiple stages of non-small cell lung cancer (NSCLC). However, a substantial proportion of patients do not undergo testing. This study evaluated the completion rates and timeliness of NGS in patients with stage II-IV NSCLC at a single academic institution with a reflex NGS testing protocol.

Next-Generation Sequencing Completion and Timeliness Using a Reflex Testing Protocol for Patients with Stage II-IV Non-Squamous, Non-Small Cell Lung Cancer

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