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Nitrosative/oxidative modifications and ageing
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DOI：10.1016/j.mad.2006.01.012.png)
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We present here a brief description of the relationships among metals, nitric oxide metabolism, and ageing. In particular, we will discuss the interactions occurring between redox (copper, iron) and non-redox (zinc) metals and nitric oxide, the metal- and nitric oxide-catalyzed formation of thiol adducts (nitrosothiols, mixed disulphides) and the possible involvement of these species in the ageing process. (c) 2006 Elsevier Ireland Ltd. All rights reserved.
Keyword:
ageing
glutathionylation
nitric oxide
nitrosylation
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