Return
Obesity in Classic Congenital Adrenal Hyperplasia: Mechanisms, Complications and Management
J
Y
M
Y
P
H
DOI:10.1111/cen.70155.png)
Abstract
En 中文
Classic congenital adrenal hyperplasia (CCAH) is an autosomal recessive genetic disorder primarily caused by 21-hydroxylase deficiency. Although the survival rate of patients has significantly improved with glucocorticoid replacement therapy, long-term use of supraphysiological doses and multiple factors inherent to the disease itself have led to obesity becoming a common metabolic complication in CCAH patients. The mechanism of obesity in CCAH patients is complex and involves multiple factors related to both treatment and the disease itself. This article provides a narrative review of the incidence, influencing factors, related complications and treatment management strategies of obesity in CCAH patients, with the aim of offering comprehensive management recommendations for clinical practice.
Keywords:
complications
congenital adrenal hyperplasia
factors
management
obesity
AI Summary
Key information extracted from the uploaded paper, including a brief overview, abstract, background, key highlights, visual analysis, and future outlook.
Journal
IF:
2.4
Papers:
7.4K
Citations:
1.3W
