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Olfaction: Allosteric modulation

delete2023-04-01
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OA
AI
S
Samuel Caton
A
Adam Dewan *
DOI:10.1016/j.cub.2023.03.046delete
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摘要

摘要

En 中文
New research indicates that the odor-evoked responses of human olfactory receptors can be enhanced via the non-competitive binding of an allosteric modulator. This modulatory mechanism adds an additional layer of complexity to the peripheral encoding of odors.
Keyword:
RECEPTORS
ODORANTS
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期刊

Current Biology 封面图
Current Biology
IF:
7.5
论文数:
2.2W
被引数:
7.8W

机构

State University System of Florida 封面图
State University System of Florida
学者数:
12.8W
论文数: 10.9W
被引数: 130
引用论文

引用论文

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Allosteric modulators enhance agonist efficacy by increasing the residence time of a GPCR in the active state
err2021-09-14
err37
errOAAI
errCao, Anne-Marinette; Quast, Robert B.; Fatemi, Fataneh; Rondard, Philippe; Pin, Jean-Philippe; Margeat, Emmanuel
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Odorant Receptor Inhibition Is Fundamental to Odor Encoding
err2020-07-01
err58
errOAAI
errPfister, Patrick; Smith, Benjamin C.; Evans, Barry J.; Brann, Jessica H.; Trimmer, Casey; Sheikh, Mushhood; Arroyave, Randy; Reddy, Gautam; Jeong, Hyo-Young; Raps, Daniel A.; Peterlin, Zita; Vergassola, Massimo; Rogers, Matthew E.
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