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On choosing heart-rate-variability (HRV) metrics to reflect vagus-nerve functioning: The construct counts, not the algorithm
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DOI：10.1016/j.biopsycho.2026.109331.png)
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Abstract
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• RespHRV debates should shift from metric preference to construct validity. • RespHRV inference should be anchored in cardiorespiratory coupling. • Blockade effects alone may not establish a purer cardiac vagal tone metric. • Respiration is inherent to RespHRV, not optional or nuisance variance. • Detrending or filtering can introduce bias in RespHRV estimation.
Keywords:
Respiratory sinus arrhythmia
Peak-valley
Spectral analysis
Moving polynomial filter
Heart rate variability
Respiration
Stationarity
Cardiac vagal
Vagus nerve
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