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Optimal initial state for fast parameter estimation in nonlinear dynamical systems

delete2019-04-01
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Q
Qiaochu Li
C
Carine Jauberthie
L
Lilianne Denis-Vidal *
Z
Zohra Cherfi
DOI:10.1016/j.cmpb.2016.07.033delete
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摘要

摘要

En 中文
Background and objective: This paper deals with the improvement of parameter estimation in terms of precision and computational time for dynamical models in a bounded error context. Methods: To improve parameter estimation, an optimal initial state design is proposed combined with a contractor. This contractor is based on a volumetric criterion and an original condition initializing this contractor is given. Based on a sensitivity analysis, our optimal initial state design methodology consists in searching the minimum value of a proposed criterion for the interested parameters. In our framework, the uncertainty (on measurement noise and parameters) is supposed unknown but belongs to known bounded intervals. Thus guaranteed state and sensitivity estimation have been considered. An elementary effect analysis on the number of sampling times is also implemented to achieve the fast and guaranteed parameter estimation. Results: The whole procedure is applied to a pharmacokinetics model and simulation results are given. Conclusions: The good improvement of parameter estimation in terms of computational time and precision for the case study highlights the potential of the proposed methodology. (C) 2016 Elsevier Ireland Ltd. All rights reserved.
Keyword:
Optimal initial state
Parameter estimation
Nonlinear systems
Contractor
Bounded noise
Interval analysis
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Computer Methods and Programs in Biomedicine 封面图
Computer Methods and Programs in Biomedicine
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被引数:
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centre national de la recherche scientifique (cnrs)
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被引数: 279
U
universite de technologie de compiegne
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