Organizing spatial pattern in limb development

William J. Brook

doi:10.1146/annurev.cellbio.12.1.161

1996-11-01

131

PRE

William J. Brook

Fernando J. Díaz‐Benjumea

Stephen M. Cohen

DOI：10.1146/annurev.cellbio.12.1.161

原文链接

摘要

En 中文

Recent studies on the development of the legs and wings of Drosophila have led to the conclusion that insect limb development is controlled by localized pattern organizing centers, analogous to those identified in vertebrate embryos. Genetic analysis has defined the events that lead to the formation of these organizing centers and has led to the identification of gene products that mediate organizer function. The possibility of homology between vertebrate and insect limbs is considered in light of recently reported similarities in patterns of gene expression and function.

Keyword:

pattern formation

Drosophila

cell interaction

signal transduction

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期刊

Annual Review of Cell and Developmental Biology

IF:

11.4

论文数:

716

被引数:

1.3W

机构

暂无机构信息

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