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P4S10-Promoted [5+1] Spiroannulation of 2-(2-Nitrophenyl)-indoles with Cyclic Ketones to Access Spirocyclic Tetrahydrocarbolines
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DOI：10.1002/adsc.70244.png)
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Abstract
En 中文
A P4S10-promoted [5 + 1] spiroannulation of 2-(2-nitrophenyl)-indoles with cyclic ketones for the preparation of spirocyclic tetrahydrocarbolines has been described. The present approach afforded a series of structurally valuable spirocyclic tetrahydrocarbolines in moderate to good yields under metal-free conditions. In this work, nitro reduction, C–N condensation, and spiroannulation were realized in one pot.
Keywords:
C–N bond
nitro reduction
spiro compound
spiroannulation
transition-metal-free
Journal
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IF:
4
Papers:
1.0W
Citations:
2.6W
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Cited Papers