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Palmitoylation modulates neutrophil anti-tumour function in liver metastasis

delete2026-08-05
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PRE
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L
Liang Zhou
J
Jun Cui *
DOI：10.1038/s42255-026-01581-1delete
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Abstract

Abstract

En 中文
How liver metastases evade immunity remains unclear. A new study published in Nature Metabolism reveals that DHHC17-driven laminin 511 palmitoylation and its subsequent secretion blunts neutrophil-mediated killing of metastatic cancer cells, uncovering a druggable immune checkpoint in the liver.

Journal

Nature Metabolism cover
Nature Metabolism
IF:
20.8
Papers:
1.6K
Citations:
1.4W

Organization

S
Sun Yat-Sen University
Scholars:
7.8K
Papers: 2.0K
Citations: 0
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