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Paper-Based Potentiometric Ion Sensing

delete2014-09-23
delete141
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OA
AI
W
W.H. Lan
X
Xu U. Zou
M
Mahiar Max Hamedi
J
Jinbo Hu
C
Claudio Parolo
E
E. Jane Maxwell
P
Philippe Bühlmann *
G
George M. Whitesides
DOI:10.1021/ac5018088delete
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摘要

摘要

En 中文
This paper describes the design and fabrication of ion-sensing electrochemical paper-based analytical devices (EPADs) in which a miniaturized paper reference electrode is integrated with a small ion-selective paper electrode (ISPE) for potentiometric measurements. Ion-sensing EPADs use printed wax barriers to define electrochemical sample and reference zones. Single-layer EPADs for sensing of chloride ions include wax-defined sample and reference zones that each incorporate a Ag/AgCl electrode. In EPADs developed for other electrolytes (potassium, sodium, and calcium ions), a PVC-based ion-selective membrane is added to separate the sample zone from a paper indicator electrode. After the addition of a small volume (less than 10 mu L) of sample and reference solutions to different zones, ion-sensing EPADs exhibit a linear response, over 3 orders of magnitude, in ranges of electrolyte concentrations that are relevant to a variety of applications, with a slope close to the theoretical value (59.2/z mV). Ion-selective EPADs provide a portable, inexpensive, and disposable way of measuring concentrations of electrolyte ions in aqueous solutions.
Keyword:
SELECTIVE ELECTRODES
ELECTROCHEMICAL DETECTION
ELECTROANALYTICAL DEVICES
CLINICAL ANALYSIS
BULK OPTODES
SENSORS
IONOPHORES
BIOSENSORS
SYSTEMS
BLOOD
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期刊

Analytical Chemistry 封面图
Analytical Chemistry
IF:
6.7
论文数:
4.7W
被引数:
15.9W

机构

H
Harvard University
学者数:
26.5W
论文数: 22.0W
被引数: 28.7W
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