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Parametric Sequential Method for MRI-Based Wall Shear Stress Quantification
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DOI：10.1109/TMI.2020.3046331.png)
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摘要
En 中文
Wall shear stress (WSS) has been suggested as a potential biomarker in various cardiovascular diseases and it can be estimated from phase-contrast Magnetic Resonance Imaging (PC-MRI) velocity measurements. We present a parametric sequential method for MRI-based WSS quantification consisting of a geometry identification and a subsequent approximation of the velocity field. This work focuses on its validation, investigating well controlled high-resolution in vitro measurements of turbulent stationary flows and physiological pulsatile flows in phantoms. Initial tests for in vivo 2D PC-MRI data of the ascending aorta of three volunteers demonstrate basic applicability of the method to in vivo.
Keyword:
Magnetic resonance imaging
Geometry
Interpolation
Biomedical imaging
Stress
Splines (mathematics)
Spatial resolution
Flow MRI
MR velocimetry
phase-contrast MRI
wall shear stress
blood flow
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