.png){kind=icon}
返回
Patterned Amyloid Materials Integrating Robustness and Genetically Programmable Functionality
.png){kind=icon}
PRE
AI
DOI：10.1021/acs.nanolett.9b02324.png)
.png){kind=icon}
原文求助.png){kind=icon}
分享.png){kind=icon}
收藏
摘要
En 中文
The precise manipulation, localization, and assembly of biological and bioinspired molecules into organized structures have greatly promoted material science and bionanotechnology. Further technological innovation calls for new patternable soft materials with the long-sought qualities of environmental tolerance and functional flexibility. Here, we report a patterned amyloid material (PAM) platform for producing hierarchically ordered structures that integrate these material attributes. This platform, combining soft lithography with generic amyloid monomer inks (consisting of genetically engineered biofilm proteins dissolved in hexafluoroisopropanol), along with methanol-assisted curing, enables the spatially controlled deposition and in situ reassembly of amyloid monomers. The resulting patterned structures exhibit spectacular chemical and thermal stability and mechanical robustness under harsh conditions. The PAMs can be programmed for a vast array of multilevel functionalities, including anchoring nanoparticles, enabling diverse fluorescent protein arrays, and serving as self-supporting porous sheets for cellular growth. This PAM platform will not only drive innovation in biomanufacturing but also broaden the applications of patterned soft architectures in optics, electronics, biocatalysis, analytical regents, cell engineering, medicine, and other areas.
Keyword:
Biofilm
genetic engineering
soft lithography
patterning
AI总结
对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。
期刊
IF:
9.1
论文数:
2.7W
被引数:
16.5W
机构
引用论文
Amyloid fibril systems reduce, stabilize and deliver bioavailable nanosized iron.png)
NATURE NANOTECHNOLOGY
NATURE NANOTECHNOLOGYIF34.9
PREAI
分享收藏Curli mediate bacterial adhesion to fibronectin via tensile multiple bondsSCIENTIFIC REPORTS
OAAI
SCIENTIFIC REPORTSIF3.9
OAAI分享收藏Nanostructured films from hierarchical self-assembly of amyloidogenic proteinsNATURE NANOTECHNOLOGYOAAI
NATURE NANOTECHNOLOGYIF34.9
OAAI分享收藏Free-Standing Gold-Nanoparticle Monolayer Film Fabricated by Protein Self-Assembly of α-Synuclein
PREAI
分享收藏
查看更多内容