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Perisomatic inhibition
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DOI：10.1016/j.neuron.2007.09.012.png)
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摘要
En 中文
Recent evidence supports the hypothesis of a functional dichotomy of perisomatic inhibition in the cerebral cortex: the parvalbumin- and cholecystokinin-containing basket cells that are specialized to control rhythm (as a clockwork) and mood (as a fine-tuning device), respectively, of network oscillations. Pathology extends this conclusion further, as the former is implicated in epilepsy and the latter in anxiety. The well-balanced cooperation of the two inhibitory systems is required for the normal network operations underlying the cognitive functions of the cerebral cortex.
Keyword:
HIPPOCAMPAL GABAERGIC SYNAPSES
LONG-TERM PLASTICITY
GAMMA-OSCILLATIONS
RAT HIPPOCAMPUS
CA1 AREA
NETWORK OSCILLATIONS
PYRAMIDAL CELLS
GABA RELEASE
ENDOCANNABINOID SYSTEM
CANNABINOID RECEPTORS
期刊
IF:
15
论文数:
1.4W
被引数:
9.9W
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分享收藏Recruitment of parvalbumin-positive interneurons determines hippocampal function and associated behavior.png)
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