.png){kind=icon}
返回
Peroxisomes: simple in function but complex in maintenance
.png){kind=icon}
OA
AI
DOI：10.1016/S0962-8924(99)01650-5.png)
.png){kind=icon}
.png){kind=icon}
分享.png){kind=icon}
收藏
摘要
En 中文
Peroxisomes compartmentalize part of the anabolic and catabolic pathways and reactions of the cell. Dysfunction of a single peroxisomal enzyme or loss of the whole peroxisomal compartment causes sporadic, but serious,, human diseases. Genetic studies in various yeasts have identified PEX genes, which are required for the maintenance of complete peroxisomes. Mutations in PEX genes have proved to be the molecular cause of several human diseases, particularly those involving loss of organelles. Peroxisomes have several properties that distinguish them from other organelles, including the import of folded proteins from the cytosol by an unknown mechanism. By discussing recent highlights from the field of peroxisome research, we aim to share with the general readership our excitement as well as the many mysteries still surrounding peroxisome function and maintenance.
Keyword:
RHIZOMELIC CHONDRODYSPLASIA PUNCTATA
SACCHAROMYCES-CEREVISIAE
MEMBRANE-PROTEIN
PTS2 RECEPTOR
ADRENOLEUKODYSTROPHY GENE
FATTY-ACIDS
HUMAN PEX7
BIOGENESIS
YEAST
IMPORT
AI总结
对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。
期刊
IF:
18.1
论文数:
3.1K
被引数:
2.0W
机构
暂无机构信息
引用论文
Nitric oxide from neuronal NOS plays critical role in cerebral capillary flow response to hypoxia
PREAI
分享收藏Derivation and validation of a prediction score for acute kidney injury in patients hospitalized with acute heart failure in a Chinese cohort.png)
Nephrology
NephrologyIF0
PREAI
分享收藏Neuroprotective action of acute estrogens: Animal models of brain ischemia and clinical implicationsSteroidsOAAI
SteroidsIF0
OAAI分享收藏
查看更多内容