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Phase-Sensitive Sodium B1 Mapping
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DOI：10.1002/mrm.22700.png)
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Quantitative sodium MRI requires accurate knowledge of factors affecting the sodium signal. One important determinant of sodium signal level is the transmit B-1 field strength. However, the low signal-to-noise ratio typical of sodium MRI makes accurate B-1 mapping in reasonable scan times challenging. A new phase-sensitive B-1 mapping technique has recently been shown to work better than the widely used dual-angle method in low-signal-to-noise ratio situations and over a broader range of flip angles. In this work, the phase-sensitive B-1 mapping technique is applied to sodium, and its performance compared to the dual-angle method through both simulation and phantom studies. The phase-sensitive method is shown to yield higher quality B-1 maps at low signal-to-noise ratio and greater consistency of measurement than the dual-angle method. An in vivo sodium B-1 map of the human breast is also shown, demonstrating the phase-sensitive method's feasibility for human studies. Magn Reson Med 65:1126-1131, 2011. (C) 2010 Wiley-Liss, Inc.
Keyword:
B-1 mapping
phase-sensitive B-1 mapping
sodium MRI
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1.2W
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