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Pineal function: Impact of microarray analysis

delete2010-01-01
delete43
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OA
AI
D
David C. Klein *
M
Michael Bailey
D
David Carter
J
Jong‐So Kim
Q
Qiong Shi
A
Anthony K. Ho
C
Constance L. Chik
P
Pascaline Gaildrat
F
Fabrice Morin
S
Surajit Ganguly
M
Martin F. Rath
M
Morten Møller
D
David Sugden
Z
Zoila G. Rangel
P
Peter J. Munson
J
Joan L. Weller
S
Steven L. Coon
DOI:10.1016/j.mce.2009.07.010delete
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摘要

摘要

En 中文
Microarray analysis has provided a new understanding of pineal function by identifying genes that are highly expressed in this tissue relative to other tissues and also by identifying over 600 genes that are expressed on a 24-h schedule. This effort has highlighted surprising similarity to the retina and has provided reason to explore new avenues of study including intracellular signaling, signal transduction, transcriptional cascades, thyroid/retinoic acid hormone signaling, metal biology, RNA splicing, and the role the pineal gland plays in the immune/inflammation response. The new foundation that microarray analysis has provided will broadly support future research on pineal function. Published by Elsevier Ireland Ltd.
Keyword:
Pineal
Microarray
Melatonin
Circadian rhythms
Cyclic AMP signaling
Immune response
Inflammation
MAP kinase
RNA splicing
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Molecular and Cellular Endocrinology 封面图
Molecular and Cellular Endocrinology
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national institutes of health (nih) - usa
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universite de rouen normandie
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