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Plasma-activated water in biomedicine: Physicochemical foundations, biomolecular mechanisms, and translational challenges
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DOI：10.1016/j.ceja.2026.101385.png)
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Abstract
En 中文
• Plasma-activated water (PAW) is a reactive liquid generated by non-thermal plasma with promising biomedical potential. • Reactive oxygen and nitrogen species (RONS) play key roles in oxidative stress, redox signaling, apoptosis, and cellular responses. • At controlled doses, PAW can also promote wound healing, cell proliferation, and anti-inflammatory responses. • Artificial intelligence and machine learning may improve plasma diagnostics, process control, and reproducibility. • Future development should focus on mechanistic understanding, standardization, and clinical translation of PAW technologies.
Keywords:
Plasma-activated water
Reactive oxygen and nitrogen species
Signaling pathway
Biomolecular response
Cells
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