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Polystyrene nanoplastics decrease molting and induce oxidative stress in adult Macrobrachium nipponense
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DOI：10.1016/j.fsi.2022.02.028.png)
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The widespread occurrence and accumulation of plastic waste have been globally recognized as a critical issue. However, few researches have evaluated the adverse effects of nanoplastics to freshwater organisms. Thus, here, the effects of polystyrene nanoplastics (PS-NP) on the physiological changes (i.e., molting) and enzyme activity of oxidative stress were investigated in the adult freshwater prawn Macrobrachium nipponense. Based on a pre-vious study and environmental microplastic concentrations, the prawn was exposed to 0, 0.04, 0.4, 4, and 40 mg/L waterborne PS-NP for 21 days. The results showed that growth and survival-related parameters were not affected by all PS-NP groups, while the molting rate were significantly decreased in the 4 and 40 mg/L PS-NP group. Meanwhile, the expression of molting-related gene (calcium-calmodulin-dependent protein kinase I, ecdysteroid receptor, and leucine-rich repeat-containing G-protein-coupled receptor 2) were significantly decreased. H2O2 content was significantly increased in all PS-NP groups relative to the control. Lower concen-trations of PS-NP increased the activity of superoxide dismutase (SOD), glutathione S-transferase (GST), and glutathione peroxidase (GSH-Px), whereas increased concentrations, decreased SOD, GST, and GSH-Px activity. These results suggest that chronic exposure to PS-NP at an environmental concentration impaired molting and induced oxidative stress in the adult river prawn Macrobrachium nipponense. The findings provided basic infor-mation for assessing the risk assessment of nanoplastics and revealing the molecular mechanisms of nanoplastics toxicity.
Keyword:
Adult Macrobrachium nipponense
Freshwater organism
Molting
Nanoplastics
Reactive oxygen species
期刊
F
IF:
3.9
论文数:
1.1W
被引数:
3.1W
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