Postherpetic Neuralgia

Robert W. Johnson

doi:10.1056/NEJMcp1403062

2014-10-16

395

PRE

Robert W. Johnson *

Andrew S.C. Rice

DOI：10.1056/NEJMcp1403062

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摘要

En 中文

A 73-year-old woman presents with persistent pain and itching in the right T10 dermatome from just above the thoracolumbar junction to the umbilicus since a documented episode of herpes zoster in the same region 1 year earlier. She describes a severe, continuous burning pain, unpredictable paroxysms of lancinating pain lasting a few seconds, and intense hypersensitivity to light tactile stimulation, such as clothing brushing against the skin. On physical examination, there are signs of cutaneous scarring throughout the right T10 dermatome, with areas of excoriation caused by scratching. She has patchy loss of tactile perception in this distribution as well as areas of pain provoked by a light brush. Acetaminophen did not help her pain. How would you manage this patient's condition?

Keyword:

NEUROPATHIC PAIN

HERPES-ZOSTER

INTRATHECAL METHYLPREDNISOLONE

PHARMACOLOGICAL MANAGEMENT

DOUBLE-BLIND

PLACEBO

GUIDELINES

ACYCLOVIR

THERAPY

EFFICACY

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期刊

New England Journal of Medicine

IF:

78.5

论文数:

2.7W

被引数:

39.7W

机构

bristol royal infirmary

学者数:

1.2K

论文数: 751

被引数: 1

University of Bristol

学者数:

3.1W

论文数: 3.0W

被引数: 5.3W

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