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PRC1 uncomplexed
DOI:10.1016/j.stemcr.2022.04.010.png)
摘要
En 中文
Epigenetic enzymes are critically involved in gene regulation during lineage commitment. In this issue of Stem Cell Reports, Zhu et al. (2022) unravel extensive redundancy between subunits of the epigenetic regulatory Polycomb Repressive Complex 1 using a systematic knockout strategy in mouse embryonic stem cells.
Keyword:
PROTEINS
POLYCOMB
AI总结
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期刊
IF:
5.1
论文数:
2.8K
被引数:
1.1W
机构
引用论文
Functional Landscape of PCGF Proteins Reveals Both RING1A/B-Dependent-and RING1A/B-Independent-Specific ActivitiesPCGF蛋白的功能景观揭示了RING1A/B依赖性和RING1A/B依赖性的特异性活性
MOLECULAR CELL
IF16.6
Synergy between Variant PRC1 Complexes Defines Polycomb-Mediated Gene Repression
MOLECULAR CELL
IF16.6
PCGF Homologs, CBX Proteins, and RYBP Define Functionally Distinct PRC1 Family Complexes
MOLECULAR CELL
IF16.6
Functional redundancy among Polycomb complexes in maintaining the pluripotent state of embryonic stem cells
STEM CELL REPORTS
IF5.1
The polycomb group protein PCGF6 mediates germline gene silencing by recruiting histone-modifying proteins to target gene promoterspolycomb组蛋白PCGF6通过将组蛋白修饰蛋白募集到靶基因启动子来介导种系基因沉默
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