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Prevalence of MSI-H/dMMR Colorectal Cancer in Japan: Data From the Clinical Study Group of the University of Osaka-Colorectal Registry

delete2026-05-24
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OA
AI
Y
Yoshihiro Morimoto
M
Mamoru Uemura *
Y
Yoshinori Kagawa
H
Hidekazu Takahashi
M
Masayuki Hiraki
Y
Yozo Suzuki
S
Shinichi Yoshioka
M
Mitsuyoshi Tei
S
Shu Okamura
Y
Yukako Mokutani
A
Atsushi Naito
S
Shinji Tokuyama
T
Takamichi Komori
A
Akinobu Yasuyama
G
Genta Sawada
Y
Yujiro Fujie
S
Shinya Yamashita
N
Naotsugu Haraguchi
Y
Yusuke Matsuura
C
Chu Matsuda
Y
Yoshinao Chinen
T
Tatsushi Shingai
K
Katsuki Danno
N
Nobuo Tanaka
K
Kazuya Sakata
K
Kohei Murata
Y
Yuichiro Doki
H
Hidetoshi Eguchi
DOI:10.1002/ags3.70226delete
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Abstract

Abstract

En 中文
Microsatellite instability-high (MSI-H) or mismatch repair-deficient (dMMR) colorectal cancer (CRC) is a distinct subtype. Although immune checkpoint inhibitors are used for advanced cases, data on its frequency and characteristics, especially in resectable Asian CRC, remain limited. This study investigated MSI-H/dMMR frequency and features in Japanese patients to support future personalized treatment strategies.
Keywords:
colorectal cancer
immune checkpoint inhibitor
japanese population
MSI-H/dMMR
prevalence
surgery
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Journal

Annals of Gastroenterological Surgery cover
Annals of Gastroenterological Surgery
IF:
3.3
Papers:
266
Citations:
2.1K

Organization

O
osaka general medical center
Scholars:
84
Papers: 66
Citations: 0
U
University of Osaka
Scholars:
4.1K
Papers: 1.3K
Citations: 1
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