PROTEIN EVOLUTION Hacking an enzyme

doi:10.1038/nchembio.2574

2018-02-14

PRE

Kristoffer E. Johansson

Jakob R. Winther *

DOI：10.1038/nchembio.2574

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摘要

En 中文

Early stages of protein evolution are inherently difficult to study. Genetic selection in Escherichia coli has now identified a life-sustaining de novo enzyme arising from a simple scaffold that is completely different from the native enzyme.

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期刊

Nature Chemical Biology

IF:

13.7

论文数:

4.8K

被引数:

3.3W

机构

University of Copenhagen

学者数:

7.6W

论文数: 6.6W

被引数: 86

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