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Proteomics-based characterization of apigenin-mediated anti-inflammatory effects in TNF-α–stimulated ARPE-19 cells

delete2026-06-20
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PRE
AI
X
Xi Chen
M
Meilin Liao
R
Ruifang Han
J
Juan Gao
P
Ping Lu
L
Liming Wang
X
Xiaomin Zhang
X
Xuan Li *
DOI：10.1016/j.intimp.2026.117048delete
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Abstract

Abstract

En 中文
• Apigenin attenuates TNF-α–induced inflammation in ARPE-19 cells. • Apigenin selectively suppresses NF-κB and MAPK signaling pathways. • Proteomics reveals global changes in inflammation-related proteins. • Key proteins linked to immune response and stress are regulated. • Apigenin shows potential for treating retinal inflammatory diseases.

Journal

International Immunopharmacology cover
International Immunopharmacology
IF:
4.7
Papers:
1.6W
Citations:
4.1W

Organization

T
tianjin eye hospital
Scholars:
51
Papers: 23
Citations: 0
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