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Provocation of occupational asthma by non-specific irritation and its relevance for the classification of chemicals as respiratory allergens: a case study of methyl methacrylate

delete2026-04-23
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M
Mark Pemberton *
S
Stuart Hindle
I
Ian Kimber
DOI:10.1016/j.yrtph.2026.106101delete
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Abstract

Abstract

En 中文
• Distinguishing new asthma from exacerbation of existing asthma is important • Human data rarely distinguish non-specific irritation from respiratory sensitisation • In vitro assays for KEs in the AOP for Respiratory sensitisation are recommended • Asthma triggered by non-specific irritations is not a basis for classifications
Keywords:
Methyl methacrylate
Non-specific respiratory irritation
Chemical respiratory allergy
Classification of occupational asthma
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Journal

Regulatory Toxicology and Pharmacology cover
Regulatory Toxicology and Pharmacology
IF:
3.5
Papers:
4.6K
Citations:
1.0W

Organization

D
dow europe gmbh
Scholars:
3
Papers: 3
Citations: 0
S
Systox Associates
Scholars:
1
Papers: 1
Citations: 0
U
University of Manchester
Scholars:
5.6W
Papers: 5.2W
Citations: 7.4W
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