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Quantitative angle-insensitive flow measurement using relative standard deviation OCT

delete2017-10-31
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OA
AI
J
Jiang Zhu
B
Buyun Zhang
Q
Qi Li
L
Ling Wang
杨
杨强 (Qiang Yang)
朱
朱竹青 (Zhuqing Zhu)
T
Tiancheng Huo
Z
Zhongping Chen *
DOI:10.1063/1.5009200delete
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摘要

摘要

En 中文
Incorporating different data processing methods, optical coherence tomography (OCT) has the ability for high-resolution angiography and quantitative flow velocity measurements. However, OCT angiography cannot provide quantitative information of flow velocities, and the velocity measurement based on Doppler OCT requires the determination of Doppler angles, which is a challenge in a complex vascular network. In this study, we report on a relative standard deviation OCT (RSD-OCT) method which provides both vascular network mapping and quantitative information for flow velocities within a wide range of Doppler angles. The RSD values are angle-insensitive within a wide range of angles, and a nearly linear relationship was found between the RSD values and the flow velocities. The RSD-OCT measurement in a rat cortex shows that it can quantify the blood flow velocities as well as map the vascular network in vivo. Published by AIP Publishing.
Keyword:
OPTICAL COHERENCE TOMOGRAPHY
CEREBRAL-BLOOD-FLOW
DOPPLER TOMOGRAPHY
SWEPT-SOURCE
SHEAR-WAVE
HUMAN SKIN
VELOCITY
DECORRELATION
ANGIOGRAPHY
REDUCTION
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期刊

Applied Physics Letters 封面图
Applied Physics Letters
IF:
3.6
论文数:
10.4W
被引数:
17.8W

机构

University of California System 封面图
University of California System
学者数:
37.7W
论文数: 33.8W
被引数: 6.6K
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