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Rapid MR elastography using selective excitations

delete2006-05-08
delete19
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K
Kevin J. Glaser
J
Joel P. Felmlee
R
Richard L. Ehman *
DOI:10.1002/mrm.20913delete
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Abstract

Abstract

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Rapid MR elastography (MRE) techniques using spatially-selective excitations to reduce acquisition times to a few seconds or less were devised and tested. The techniques included reduced field of view (rFOV) MRE and ID MRE (beam MRE) using 2D spatially selective RF excitations for gradient-echo (GRE) applications and intersecting 90 degrees and 180 degrees slice-selective excitations for spin-echo (SE) applications. It was shown that scan times could be reduced by a factor of 8 using rFOV MRE, and by 64 using beam MRE, while still obtaining stiffness estimates comparable to full-FOV MRE. Results were shown in gel phantom experiments as well as in the case of a preserved postmortem breast tissue specimen with a stiff lesion. These methods can be used to more rapidly interrogate regions of interest (ROls) in tissue to quickly obtain information about the viscoelastic properties of that tissue.
Keywords:
magnetic resonance elastography
selective excitation
tissue characterization
reduced FOV
beam elastography
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Journal

Magnetic Resonance in Medicine cover
Magnetic Resonance in Medicine
IF:
3
Papers:
1.2W
Citations:
3.1W

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