Reactors for flow biocatalysis: classification;  performance;  and prospects

doi:10.1039/D5RE00260E

2025-09-04

PRE

张少斌 (Shaobin Zhang) *

余子夷 (Ziyi Yu) *

DOI：10.1039/D5RE00260E

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摘要

En 中文

流态生物催化已作为一种有前景的替代传统批次工艺的方法出现，具有提高能源效率、增强反应控制和减少废物产生的优势。本文综述了流态生物催化领域的最新进展，重点关注系统设计、酶处理策略和催化性能。基于酶的保留，这些系统被广泛分为两类：使用游离酶的流态生物催化，其中酶与产物共洗脱；以及使用固定化酶的流态生物催化，其中酶在反应器内固定化。后者进一步细分为壁涂型和填充型系统，包括多层涂层、接枝表面和整体式结构。通过讨论在药物合成、精细化学品和环境修复中的代表性应用，阐述了这些技术的实际影响。最后，概述了未来展望，强调了载体材料创新、反应器设计优化和数据驱动过程控制对于进一步推动流态生物催化发展的潜力。

期刊

Reaction Chemistry and Engineering

IF:

3.1

论文数:

1.9K

被引数:

5.0K

机构

sinopec carbon industry technology co., ltd, nanjing 210000, china

学者数:

论文数: 1

被引数: 0

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