.png){kind=icon}
返回
Recent Progress in RXLR Effector Research
.png){kind=icon}
OA
AI
DOI：10.1094/MPMI-01-15-0022-CR.png)
.png){kind=icon}
.png){kind=icon}
分享.png){kind=icon}
收藏
摘要
En 中文
Some of the most devastating oomycete pathogens deploy effector proteins, with the signature amino acid motif RXLR, that enter plant cells to promote virulence. Research on the function and evolution of RXLR effectors has been very active over the decade that has transpired since their discovery. Comparative genomics indicate that RXLR genes play a major role in virulence for Phytophthora and downy mildew species. Importantly, gene-for-gene resistance against these oomycete lineages is based on recognition of RXLR proteins. Comparative genomics have revealed several mechanisms through which this resistance can be broken, most notably involving epigenetic control of RXLR gene expression. Structural studies have revealed a core fold that is present in the majority of RXLR proteins, providing a foundation for detailed mechanistic understanding of virulence and avirulence functions. Finally, functional studies have demonstrated that suppression of host immunity is a major function for RXLR proteins. Host protein targets are being identified in a variety of plant cell compartments. Some targets comprise hubs that are also manipulated by bacteria and fungi, thereby revealing key points of vulnerability in the plant immune network.
Keyword:
LATE BLIGHT RESISTANCE
PLANT IMMUNE-SYSTEM
PHYTOPHTHORA-INFESTANS
HYALOPERONOSPORA-ARABIDOPSIDIS
CELL-DEATH
SEQUENCE POLYMORPHISMS
PATHOGEN EFFECTORS
NONHOST RESISTANCE
GENOME EVOLUTION
CAUSES GAIN
AI总结
对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。
期刊
IF:
24.1
论文数:
6.9K
被引数:
2.8W
机构
暂无机构信息
引用论文
Deletion of the Phytophthora sojae Avirulence Gene Avr1d Causes Gain of Virulence on Rps1d.png)
molecular plant
molecular plantIF3.4
PREAI
分享收藏Conserved C-terminal motifs required for avirulence and suppression of cell death by Phytophthora sojae effector Avr1bPLANT CELLOAAI
PLANT CELLIF11.6
OAAI分享收藏Multiple Candidate Effectors from the Oomycete Pathogen Hyaloperonospora arabidopsidis Suppress Host Plant ImmunityPLOS PATHOGENSOAAI
PLOS PATHOGENSIF4.9
OAAI分享收藏An Effector-Targeted Protease Contributes to Defense against Phytophthora infestans and Is under Diversifying Selection in Natural Hosts效应物靶向蛋白酶有助于防御疫霉，并且在自然宿主中处于多样化选择之下PLANT PHYSIOLOGYOAAI
PLANT PHYSIOLOGYIF6.9
OAAI分享收藏
查看更多内容