.png){kind=icon}
返回
Reductive Stress: Neglected Science
.png){kind=icon}
PRE
AI
DOI：10.1089/ars.2020.8114.png)
.png){kind=icon}
原文求助.png){kind=icon}
分享.png){kind=icon}
收藏
摘要
En 中文
Over the past six decades, the concept of redox was focused on one arm of the redox spectrum: oxidative stress. In fact, a vast majority of experimental and clinical studies addressing redox mechanisms claimed oxidative stress as the culprit for acute or chronic disease conditions. Recent studies have documented that reactive oxygen species (ROS) are crucial signaling molecules facilitating various cellular processes. Thus, abrogation of these key ROS signaling through abundant antioxidant systems will result in detrimental effects. This Forum highlights the emerging concepts and related mechanisms of the other extreme of the redox spectrum, known as reductive stress (RS). The Forum including original research and review articles discusses the causes and consequences of RS in various biological and pathological conditions such as metabolism, cancer, drug resistance, cardiac hypertrophy, and microbial adaptations.
Keyword:
reductive stress
Nrf2 signaling
metabolic stress
mycobacterium
cancer and drug resistance
AI总结
对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。
期刊
A
IF:
6.1
论文数:
4.7K
被引数:
2.4W
机构
引用论文
Nrf2 deficiency prevents reductive stress-induced hypertrophic cardiomyopathy.png)
CARDIOVASCULAR RESEARCH
OAAI
CARDIOVASCULAR RESEARCHIF13.3
OAAI分享收藏
没有更多内容
没有更多内容