Reply to: Utilizing foundation models for developing clinical tools

Juzhao Zhang

doi:10.1038/s41746-025-02066-3

2025-11-18

DOI：10.1038/s41746-025-02066-3

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摘要

En 中文

本回复针对Chan等人对我们先前研究的评论，澄清了基础模型（如RETFound）的使用、商业数据来源/匿名性以及DeLong检验结果。我们强调，经过SDEDS微调的RETFound在性能上优于商业模型，并承认需要进行进一步的测试，同时参考了一个早期的基准值。

Keyword:

foundation models

clinical tools

RETFound

DeLong test

benchmarking

AI总结

对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。

期刊

npj Digital Medicine

IF:

15.1

论文数:

3.5K

被引数:

1.5W

机构

tong ji university

学者数:

论文数: 2

被引数: 0

引用论文

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415

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Comparing the Areas under Two or More Correlated Receiver Operating Characteristic Curves: A Nonparametric Approach 比较两个或多个相关接收器工作特性曲线下的区域: 非参数方法

Biometrics

IF0

1988-09-01

PREAI

Elizabeth R. DeLong; David M. DeLong; Daniel L. Clarke-Pearson

Development and Validation of a Multimodal Multitask Vision Foundation Model for Generalist Ophthalmic Artificial Intelligence

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IF0

2024-11-27

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npj Digital Medicine

IF15.1

2025-06-21

OAAI

Danli Shi; Weiyi Zhang; Jiancheng Yang; Siyu Huang; Xiaolan Chen; Pusheng Xu; Kai Jin; Shan Lin; Jin Wei; Mayinuer Yusufu; Shunming Liu; Qing Zhang; Zongyuan Ge; Xun Xu; Mingguang He

A foundation model for generalizable disease detection from retinal images

Nature

IF48.5

2023-09-13

OAAI

Yukun Zhou; Mark A. Chia; Siegfried K. Wagner; Murat S. Ayhan; Dominic J. Williamson; Robbert R. Struyven; Timing Liu; Moucheng Xu; Mateo G. Lozano; Peter Woodward-Court; Yuka Kihara; Andre Altmann; Aaron Y. Lee; Eric J. Topol; Alastair K. Denniston; Daniel C. Alexander; Pearse A. Keane

RETFound-enhanced community-based fundus disease screening: real-world evidence and decision curve analysis

NPJ DIGITAL MEDICINE

IF15.1

2024-04-30

OAAI

Cheng, Tianhao; Xu, Yi; Lu, Lina; He, Jiangnan; Yu, Tao; Peng, Yajun; Zou, Haidong; Ma, Yingyan

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