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Reshaping the Ventricle From Within

delete2023-01-01
delete10
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OA
AI
C
Christopher G. Bruce
J
Jaffar M. Khan
T
Toby Rogers
D
Dursun Korel Yildirim
A
Andrea E. Jaimes
F
Felicia Seemann
M
Marcus Y. Chen
K
Kendall O’Brien
D
Daniel A. Herzka
W
William H. Schenke
M
Michael Eckhaus
A
Adrienne Campbell‐Washburn
V
Vasilis Babaliaros
A
Adam B. Greenbaum
R
Robert J. Lederman *
DOI:10.1016/j.jacbts.2022.07.002delete
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摘要

摘要

En 中文
MIRTH (Myocardial Intramural Remodeling by Transvenous Tether) is a transcatheter ventricular remodeling procedure. A transvenous tension element is placed within the walls of the beating left ventricle and shortened to narrow chamber dimensions. MIRTH uses 2 new techniques: controlled intramyocardial guidewire navigation and EDEN (Electrocardiographic Radial Depth Navigation). MIRTH caused a sustained reduction in chamber dimensions in healthy swine. Midventricular implants approximated papillary muscles. MIRTH shortening improved myocardial contractility in cardiomyopathy in a dose-dependent manner up to a threshold beyond which additional shortening reduced performance. MIRTH may help treat dilated cardiomyopathy. Clinical investigation is warranted. (J Am Coll Cardiol Basic Trans Science 2023;8:37-50) Published by Elsevier on behalf of the American College of Cardiology Foundation. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
Keyword:
cardiac repair
cardiomyopathy
heart failure
etiology
mortality
surgery
surgical ventricular restoration
ventricular remodeling
ventriculoplasty

期刊

JACC-Basic to Translational Science 封面图
JACC-Basic to Translational Science
IF:
7.2
论文数:
1.3K
被引数:
4.3K

机构

N
national institutes of health (nih) - usa
学者数:
10.3W
论文数: 8.2W
被引数: 111
M
Medstar Washington Hospital Center
学者数:
2.9K
论文数: 2.2K
被引数: 2
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