Restless legs syndrome determines whether periodic limb movements are associated with altered lipid profiles in sleep-disordered breathing

Alen Juginovic

doi:10.1016/j.sleep.2026.109109

Restless legs syndrome determines whether periodic limb movements are associated with altered lipid profiles in sleep-disordered breathing

2026-07-05

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Alen Juginovic *

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Laura Rodman

DOI：10.1016/j.sleep.2026.109109

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Periodic limb movements (PLM) during sleep are common in sleep-disordered breathing (SDB), but their independent association with cardiometabolic markers remains unclear. Restless legs syndrome (RLS), which frequently co-occurs with PLM, may modify this relationship. We investigated whether PLM are independently associated with cardiometabolic risk in SDB, and whether RLS modifies these associations.

Restless legs syndrome determines whether periodic limb movements are associated with altered lipid profiles in sleep-disordered breathing

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