.png){kind=icon}
返回
Retinal detachment
.png){kind=icon}
PRE
AI
DOI：10.1038/s41572-024-00501-5.png)
.png){kind=icon}
原文求助.png){kind=icon}
分享.png){kind=icon}
收藏
摘要
En 中文
Retinal detachment (RD) occurs when the neurosensory retina, the neurovascular tissue responsible for phototransduction, is separated from the underlying retinal pigment epithelium (RPE). Given the importance of the RPE for optimal retinal function, RD invariably leads to decreased vision. There are three main types of RD: rhegmatogenous, tractional and exudative (also termed serous) RD. In rhegmatogenous RD, one or more retinal breaks enable vitreous fluid to enter the subretinal space and separate the neurosensory retina from the RPE. In tractional RD, preretinal, intraretinal or subretinal membranes contract and exert tangential forces and elevate the retina from the underlying RPE. Finally, in exudative RD, an underlying inflammatory condition, vascular abnormality or the presence of a tumour causes exudative fluid to accumulate in the subretinal space, exceeding the osmotic pump function of the RPE. The surgical management of RD usually involves pars plana vitrectomy, scleral buckling or pneumatic retinopexy. The approach taken often depends on patient characteristics as well as on practitioner experience and clinical judgement. Advances in surgical technology and continued innovation have improved outcomes for many patients. However, even if retinal re-attachment is achieved, some patients still experience decreased vision or other visual symptoms, such as metamorphopsia, that diminish their quality of life. Continued research in the areas of neuroprotection and retinal biology as well as continued surgical innovation are necessary to enhance therapeutic options and outcomes for these patients. Retinal detachment describes the separation of the neurosensory retina from the underlying retinal pigment epithelium, leading to impaired vision or vision loss. This Primer discusses the epidemiology, pathophysiology, diagnosis and management of this disorder and highlights future research directions.
Keyword:
QUALITY-OF-LIFE
PARS-PLANA VITRECTOMY
PROLIFERATIVE VITREORETINOPATHY
SURGICAL-MANAGEMENT
SCLERAL BUCKLE
COATS-DISEASE
SILICONE OIL
RISK-FACTORS
PNEUMATIC RETINOPEXY
CLINICAL-FEATURES
期刊
N
IF:
60.6
论文数:
651
被引数:
3.8W
机构
引用论文
Phosphorus-containing copolyesters: The effect of ionic group and its analogous phosphorus heterocycles on their flame-retardant and anti-dripping performances.png)
Polymer
PolymerIF0
PREAI
分享收藏Highly efficient p-i-n perovskite solar cells that endure temperature variations可承受温度变化的高效p-i-n钙钛矿太阳能电池Science
OAAI
ScienceIF0
OAAI分享收藏Acute posterior vitreous detachment: the predictive value of vitreous pigment and symptomatology
OAAI
OAAI分享收藏
查看更多内容