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Sad Mood in Late-Life Depression Correlates With Reduced Thickness in Orbitofrontal Cortex
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DOI:10.1002/gps.70218.png)
Abstract
En 中文
Late-life depression (LLD) is a heterogeneous psychiatric condition characterized by a wide range of psychopathological symptoms and associated with functional and structural abnormalities in brain networks implicated in mood and cognitive regulation. This cross-sectional study investigated the relationship between specific depressive symptom dimensions and cortical brain measures, as assessed by magnetic resonance imaging, in a sample of 87 community-dwelling older adults with depression.
Keywords:
depressive symptom dimensions
late-life depression
magnetic resonance imaging
orbitofrontal cortex
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