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Safety of swallowed corticosteroids and their influence on the hypothalamic–pituitary–adrenal gland axis and on markers of bone resorption and formation in patients with eosinophilic esophagitis

delete2026-07-06
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PRE
AI
J
Jesús Sánchez César *
V
Valentín Roales
M
Martín Cuesta
A
Andrea López Rodríguez
C
Constanza Ciriza de los Ríos
J
Juan Luis Mendoza Hernández
DOI:10.1002/bcp.70678delete
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Abstract

Abstract

En 中文
Corticosteroids have side effects like adrenal insufficiency (AI) and bone decalcification, amongst others. Swallowed formulations appear to be les harmful. Our aim is to study the effects of orodispersable budesonide used in patients with eosinophilic esophagitis (EoE) on the hypothalamic-pituitary-adrenal axis, by using a test with higher sensitivity than measuring basal cortisol levels, and on bone resorption and formation.
Keywords:
adrenal insufficiency
eosinophilic Esophagitis
swallowed corticosteroids

Journal

British Journal of Clinical Pharmacology cover
British Journal of Clinical Pharmacology
IF:
3
Papers:
8.5K
Citations:
1.8W

Organization

H
Hospital Clinico San Carlos and IDISSC
Scholars:
6
Papers: 2
Citations: 0
H
hospital clínico san carlos
Scholars:
439
Papers: 164
Citations: 0
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