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α-Satellite RNA maintains centromeric cohesion through R-loops

delete2026-08-05
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PRE
AI
L
Lu Yang
Q
Qian Zhang
Z
Zhen Teng
E
Erin Moran
Z
Zhen Lin
P
P. Todd Stukenberg
H
Hong Liu *
DOI:10.1016/j.molcel.2026.07.023delete
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Abstract

Abstract

En 中文
• α-Satellite RNA forms in cis and in trans R-loops at human centromeres • α-Satellite RNA is required for maintaining centromeric cohesion • α-Satellite RNA-formed R-loops are required for maintaining centromeric cohesion • α-Satellite RNA and its formed R-loops recruit Shugoshin 1 to inner centromeres

Journal

Molecular Cell cover
Molecular Cell
IF:
16.6
Papers:
1.0W
Citations:
8.5W

Organization

T
Tulane University School of Medicine
Scholars:
73
Papers: 31
Citations: 0
U
university of virginia
Scholars:
3.7K
Papers: 1.7K
Citations: 0
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