scafari: exploring scDNA-seq data

Sophie-Marie Wind

doi:10.1093/bioinformatics/btaf477

2025-09-01

DOI：10.1093/bioinformatics/btaf477

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近年来单细胞测序技术的进展使得人们不仅能够分析单个细胞的表达模式，还能利用尖端技术——单细胞DNA测序——深入了解单个细胞的基因组。Mission Bio公司凭借其Tapestri平台，是这项技术的少数供应商之一。然而，目前适用于该类型数据的用户友好型处理和质量分析开源软件非常有限。我们在此介绍scafari，这是一款提供易于使用的质量控制工具，并支持探索性变异分析和可视化的软件。可用性与实现：scafari已作为R Bioconductor软件包实现，包含一个shiny应用程序，可从https://bioconductor.org/packages/scafari获取。

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Otto von Guericke University

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