.png){kind=icon}
返回
Self-assembling biomolecules for biosensor applications
.png){kind=icon}
OA
AI
DOI：10.1186/s40824-023-00466-8.png)
.png){kind=icon}
.png){kind=icon}
分享.png){kind=icon}
收藏
摘要
En 中文
Molecular self-assembly has received considerable attention in biomedical fields as a simple and effective method for developing biomolecular nanostructures. Self-assembled nanostructures can exhibit high binding affinity and selectivity by displaying multiple ligands/receptors on their surface. In addition, the use of supramolecular structure change upon binding is an intriguing approach to generate binding signal. Therefore, many self-assembled nanostructure-based biosensors have been developed over the past decades, using various biomolecules (e.g., peptides, DNA, RNA, lipids) and their combinations with non-biological substances. In this review, we provide an overview of recent developments in the design and fabrication of self-assembling biomolecules for biosensing. Furthermore, we discuss representative electrochemical biosensing platforms which convert the biochemical reactions of those biomolecules into electrical signals (e.g., voltage, ampere, potential difference, impedance) to contribute to detect targets. This paper also highlights the successful outcomes of self-assembling biomolecules in biosensor applications and discusses the challenges that this promising technology needs to overcome for more widespread use.
Keyword:
Molecular self-assembly
Supramolecular biosensor
Electrochemical biosensor
AI总结
对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。
期刊
IF:
9.6
论文数:
718
被引数:
4.9K
机构
引用论文
Environmentally Induced Epigenetic Transgenerational Inheritance of Altered Sertoli Cell Transcriptome and Epigenome: Molecular Etiology of Male Infertility.png)
PLoS ONEOAAI
PLoS ONEIF0
OAAI分享收藏Recent Progress in Electrochemical Aptasensors: Construction and Application电化学传感器的最新进展: 构建和应用CHEMOSENSORS
OAAI
CHEMOSENSORSIF3.7
OAAI分享收藏Impedimetric transducers based on interdigitated electrode arrays for bacterial detection - A review
PREAI
分享收藏A label-free and self-assembled electrochemical biosensor for highly sensitive detection of cyclic diguanylate monophosphate (c-di-GMP) based on RNA riboswitch基于RNA核糖开关的无标记自组装电化学生物传感器，用于高灵敏检测环二鸟苷酸单磷酸酯 (c-di-gmp)
PREAI
分享收藏
查看更多内容