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Seroprevalence of Mycobacterium leprae antibodies among school children in Indonesia in 2023: a cross-sectional study

delete2026-05-27
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OA
AI
L
Louise Pierneef
M
Munawir Muhammad
G
Gaby Wassenaar
D
Daniel Edbert
H
Hana Krismawati
S
Sitti Wahyuni
S
Soegianto Ali
M
Maria Mardalena Martini Kaisar
P
Paul Corstjens
A
Annemieke Geluk *
DOI:10.1016/j.lansea.2026.100779delete
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Abstract

Abstract

En 中文
Leprosy remains a significant public health issue in endemic regions, including areas in Indonesia. Transmission of Mycobacterium leprae (M. leprae) continues as clear from the almost stable annual number of new leprosy cases amongst which around 5% are children. To interrupt transmission of M. leprae, it is essential to identify and treat infection sources. This study aimed to assess anti-M. leprae phenolic glycolipid-I (PGL-I) IgM seroprevalence among school-aged children in rural and urban Indonesia, as a proxy for recent transmission. Additionally, associations between seropositivity and gender, socioeconomic status (SES), and helminth infection were investigated.
Keywords:
Children
Helminths
M. leprae infection
PGL-I QURapid
Rural vs. urban
Transmission
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Journal

T
The Lancet Regional Health - Southeast Asia
IF:
0
Papers:
93
Citations:
0

Organization

Atma Jaya Catholic University of Indonesia cover
Atma Jaya Catholic University of Indonesia
Scholars:
40
Papers: 35
Citations: 224
H
Hasanuddin University
Scholars:
380
Papers: 137
Citations: 1.0K
L
leiden university medical center
Scholars:
1.2K
Papers: 396
Citations: 0
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