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Seroprevalence of Mycobacterium leprae antibodies among school children in Indonesia in 2023: a cross-sectional study
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DOI:10.1016/j.lansea.2026.100779.png)
Abstract
En 中文
Leprosy remains a significant public health issue in endemic regions, including areas in Indonesia. Transmission of Mycobacterium leprae (M. leprae) continues as clear from the almost stable annual number of new leprosy cases amongst which around 5% are children. To interrupt transmission of M. leprae, it is essential to identify and treat infection sources. This study aimed to assess anti-M. leprae phenolic glycolipid-I (PGL-I) IgM seroprevalence among school-aged children in rural and urban Indonesia, as a proxy for recent transmission. Additionally, associations between seropositivity and gender, socioeconomic status (SES), and helminth infection were investigated.
Keywords:
Children
Helminths
M. leprae infection
PGL-I QURapid
Rural vs. urban
Transmission
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