.png){kind=icon}
返回
Sickle cell disease classification using deep learning
.png){kind=icon}
OA
AI
DOI：10.1016/j.heliyon.2023.e22203.png)
.png){kind=icon}
.png){kind=icon}
分享.png){kind=icon}
收藏
摘要
En 中文
This paper presents a transfer and deep learning based approach to the classification of Sickle Cell Disease (SCD). Five transfer learning models such as ResNet-50, AlexNet, MobileNet, VGG-16 and VGG-19, and a sequential convolutional neural network (CNN) have been implemented for SCD classification. ErythrocytesIDB dataset has been used for training and testing the models. In order to make up for the data insufficiency of the erythrocytesIDB dataset, advanced image augmentation techniques are employed to ensure the robustness of the dataset, enhance dataset diversity and improve the accuracy of the models. An ablation experiment using Random Forest and Support Vector Machine (SVM) classifiers along with various hyperparameter tweaking was carried out to determine the contribution of different model elements on their predicted accuracy. A rigorous statistical analysis was carried out for evaluation and to further evaluate the model's robustness, an adversarial attack test was conducted. The experimental results demonstrate compelling performance across all models. After performing the statistical tests, it was observed that MobileNet showed a significant improvement (p = 0.0229), while other models (ResNet-50, AlexNet, VGG-16, VGG-19) did not (p > 0.05). Notably, the ResNet-50 model achieves remarkable precision, recall, and F1-score values of 100 % for circular, elongated, and other cell shapes when experimented with a smaller dataset. The AlexNet model achieves a balanced precision (98 %) and recall (99 %) for circular and elongated shapes. Meanwhile, the other models showcase competitive performance.
Keyword:
Sickle cell disease
Classification
Ablation experiment
Deep learning model
Machine learning classifier
AI总结
对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。
期刊
IF:
3.6
论文数:
3.8W
被引数:
10.5W
机构
引用论文
分享收藏Biomimetic anisotropic polymeric nanoparticles coated with red blood cell membranes for enhanced circulation and toxin removal.png)
SCIENCE ADVANCESOAAI
SCIENCE ADVANCESIF12.5
OAAI分享收藏分享收藏Classification of red cell dynamics with convolutional and recurrent neural networks: a sickle cell disease case studySCIENTIFIC REPORTSOAAI
SCIENTIFIC REPORTSIF3.9
OAAI分享收藏
查看更多内容