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Significant decrease in injection risk behaviours among participants in a needle exchange programme
DOI:10.1080/23744235.2020.1727002.png)
摘要
En 中文
Background and aims: Sharing of unsterile injection equipment contributes to transmission of hepatitis C virus (HCV), HIV and hepatitis B virus (HBV) among people who inject drugs (PWID) but is largely preventable through needle exchange programmes (NEP). Sweden has been one of the last countries in Europe to scale up access to NEP for PWID, who consequently have high prevalence rates of HCV and HIV. The aim of the study was to investigate demographic and drug-related determinants of injection risk behaviours, sharing of needle/syringe and paraphernalia, and patterns of change over time in subgroups of PWID participating in the Stockholm NEP. Methods: The Stockholm NEP started in 2013 as the first formal NEP in the region. A total of 2860 PWID were included in this prospective open cohort study. The association between demographic and drug-related determinants and injection risk behaviours were analysed at baseline and followed up at 6, 12, 24, 36 and 48 months post-enrolment. Results: The following factors were associated with high levels of injection risk behaviours at inclusion: female gender, homelessness, low education level, younger age, amphetamine use, not in opioid substitution therapy (OST), being HIV negative and being HCV positive. We found an overall significant decrease in injection risk behaviours over time among participants. Not previously investigated in depth, we found that subgroups of participants varied in degrees of injection risk behaviour reduction over time and that women decreased injection risk behaviours faster than men. Enrolment in OST, HIV positive and age Conclusions: In this prospective cohort study over 4 years, we found that NEP participation was associated with a significant decrease in injection risk behaviours.
Keyword:
Injection risk behaviour
HIV
hepatitis C
people who inject drugs
needle exchange programme
harm reduction
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期刊
IF:
2.3
论文数:
1.6K
被引数:
2.3K
机构
引用论文
Global prevalence of injecting drug use and sociodemographic characteristics and prevalence of HIV, HBV, and HCV in people who inject drugs: a multistage systematic review注射吸毒者的全球注射吸毒率和社会人口统计学特征以及HIV,HBV和HCV的患病率: 多阶段系统评价
The impact of needle and syringe provision and opiate substitution therapy on the incidence of hepatitis C virus in injecting drug users: pooling of UK evidence
ADDICTION
IF5.3
Global, regional, and country-level estimates of hepatitis C infection among people who have recently injected drugs最近注射毒品的人群中丙型肝炎感染的全球,区域和国家一级的估计
ADDICTION
IF5.3
Prevalence of hepatitis C and pre-testing awareness of hepatitis C status in 1500 consecutive PWID participants at the Stockholm needle exchange program
INFECTIOUS DISEASES
IF2.3
Factors associated with persistent high-risk syringe sharing in the presence of an established needle exchange programme
AIDS
IF3.1

