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Simulation-based inference with approximately correct parameters via maximum entropy

delete2022-04-27
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OA
AI
R
Rainier Barrett
M
Mehrad Ansari
G
Gourab Ghoshal
A
Andrew Dickson White *
DOI:10.1088/2632-2153/ac6286delete
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摘要

摘要

En 中文
从观察结果推断模拟器的输入参数是从流行病学到分子动力学应用的关键挑战。在这里,我们展示了一种在稀疏数据和近似正确模型的情况下的简单方法,这在尝试使用现有模型来推断具有观察数据的潜在变量时很常见。该方法基于最大熵 (MaxEnt) 原理,并且可证明使潜在联合分布中的最小变化适合新数据。此方法不需要似然或模型导数,并且其拟合对先验强度不敏感,从而消除了将观察到的数据拟合与先验信念进行平衡的需要。该方法需要数据符合期望的ansatz,这在一些设置中是真实的,并且在具有很少数据点的所有设置中可能是合理的。该方法基于样本重新加权,因此其渐近运行时间与先验分布维数无关。我们演示了这种MaxEnt方法,并与三个系统中的其他无似然推理方法进行了比较: 在引力场中移动的点粒子,流行病传播的隔室模型和蛋白质的分子动力学模拟。
Keyword:
simulation-based inference
maximum entropy
likelihood-free
derivative-free

期刊

M
Machine Learning-Science and Technology
IF:
4.6
论文数:
1.1K
被引数:
3.4K

机构

U
University of Rochester
学者数:
2.6W
论文数: 2.1W
被引数: 2.2W
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